Capsaicin® (Capzasin-P®, Icy Hot®, Rid-a-Pain®, Zostrix®) is used to help
relieve pain in the muscle or joints. It is also used for different types of nerve pain, such
as pain due to nerve problems in people with diabetes. Capsaicin skin preparations are
available from many different manufacturers.
Do not use a product like this if you have any of the following:
broken skin
irritated skin
an unusual or allergic reaction to capsaicin, hot peppers, other medicines, foods, dyes,
or preservatives
breast-feeding
pregnant or trying to get pregnant
How To Use This Medicine
Follow the directions on the label. Capsaicin should be used 3 to 4 times per day. Less
frequent use will decrease the effect of capsaicin. Rub the cream or gel into the painful
area until there is little or no visible cream (or gel) left on the skin surface. Unless you
are using capsaicin for arthritis of the hands, you should wash your hands after you apply
the cream or gel. If you are using capsaicin for arthritis of the hands, do not wash your
hands for at least 30 minutes after using this medicine.
Wear gloves when applying capsaicin cream
Do not apply it immediately after a hot bath or shower or use it with a heating pad
Avoid getting capsaicin cream in eyes and other mucus membranes or broken skin
The safety of capsaicin cream in pregnant or nursing women hasn't been established
Contact your pediatrician or health care professional regarding the use of this medicine in
children. Special care may be needed.
Precautions While on this Medicine
Do not use a product like this if you have any of the following:
broken skin
irritated skin
an unusual or allergic reaction to capsaicin, hot peppers, other medicines, foods, dyes,
or preservatives
breast-feeding
pregnant or trying to get pregnant
A Note of Caution - At least one article in the scientific literature indicates that there
have been no large scale studies of long term effects of capsaicin in the digestive tract of
patients whose health has been compromised by surgery or long term neuropathy. An article
summarized in Science/Health Abstracts Vol. 5, No. 3, indicates
that capsaicin can have significant toxic effects within the body.
If You Miss A Dose
If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use
only that dose. Do not use double or extra doses.
Side Effects
Side effects that you should report to your prescriber or health care professional as soon
as possible:
breakdown of your skin
cough
Side effects that usually do not require medical attention (report to your prescriber or
health care professional if they continue or are bothersome):
burning or stinging of skin at site of application
warm sensation at site of application
Side effects other than those listed here may also occur. Talk to your doctor about any
side effect that seems unusual or that is especially bothersome.
Drug Interactions
There are no known drug interactions with capsaicin.